Zinc messenger

Zinc is a novel intracellular second messenger

Zinc is an essential trace element required for enzymatic activity and for maintaining the conformation of many transcription factors; thus, zinc homeostasis is tightly regulated. Although zinc affects several signaling molecules and may act as a neurotransmitter, it remains unknown whether zinc acts as an intracellular second messenger capable of transducing extracellular stimuli into intracel...

Zinc as a second messenger of mitogenic induction. Effects on diadenosine tetraphosphate (Ap4A) and DNA synthesis.

DNA synthesis and adenosine(5')tetraphosphate(5')adenosine (Ap4A) levels decrease in cells treated with EDTA. The inhibitory effect of EDTA can be reversed with micromolar amounts of ZnCl2. ZnCl2 in micromolar concentrations also inhibits Ap4A hydrolase and stimulates amino acid-dependent Ap4A synthesis, suggesting that Zn2+ is modulating intracellular Ap4A pools. Serum addition to G1-arrested ...

The Messenger of God, Managing the Quarrels in Medina

Conflict and quarrel may be counted essential for human societies. In some cases, lack of wise management leads quarrels to crisis in such a way that its foundation comes to be destroyed. The importance of the problem has led scholars in the field of management to deal with it and study to find a solution. This paper has studied the solutions of the Prophet for the quarrels of peoples in Medina...

-Second Messenger-

Genetic polymorphisms and environmental factors work with and against each other to affect neurodevelopment and the delicate balance of neurotransmitters that underlie psychiatric disorders. This article explores the complex nature of gene-gene and gene-environment interactions and the implications for diagnosis and treatment of disease. As an example of this dynamic relationship, the gene for ...

Messenger RNA.